Career

Working at Grove

We are looking for energetic, innovative team members with a strong enthusiasm for collaborating in a dynamic, fast-paced, multidisciplinary environment.

Current openings

Grove Biopharma, Inc.

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Benefits and Perks

The benefits of working at Grove Biopharma extend far beyond the traditional packages advertised by other companies. We make everyday life convenient by offering on-site resources. We encourage employees to achieve their highest potential by providing recognition and rewards for outstanding achievements, educational assistance programs, and multiple career pathways.

  • Health Savings Account
  • Employee Assistance Program
  • $300 Commuter Stipend
  • $50 Mobile Stipend
  • $500 Wellness Account
  • Free Onsite Gym
  • Company Sponsored Social Events
  • 401K Plan with 4% Entrada match
  • Entrada Swag & Gear
  • Wednesday Company Lunches
  • Generous Parental Leave
  • Caregiver Concierge Services

Grove Biopharma is located in Chicago’s Fulton Market—the city’s epicenter for technology and innovation and one of its fastest-growing neighborhoods, with access to a vibrant work/live/play community, top-tier universities, medical centers and service providers. Our offices and labs are housed within the Portal Innovations Fulton Labs location, an expansive space designed to provide best-in-class, fully equipped wet/dry lab and work space, “Smart” windows to regulate glare and temperature, optimize natural light, and frame stunning Chicago skyline views. Generous common areas including a “chef’s kitchen”, rooftop patio, and state of the art fitness facility foster collaboration and comfort.

Grove Biopharma is located in Chicago’s Fulton Market—the city’s epicenter for technology and innovation and one of its fastest-growing neighborhoods, with access to a vibrant work/live/play community, top-tier universities, medical centers and service providers. Our offices and labs are housed within the Portal Innovations Fulton Labs location, an expansive space designed to provide best-in-class, fully equipped wet/dry lab and work space, “Smart” windows to regulate glare and temperature, optimize natural light, and frame stunning Chicago skyline views. Generous common areas including a “chef’s kitchen”, rooftop patio, and state of the art fitness facility foster collaboration and comfort.

Open Positions

Senior Scientist, Bioanalytical Chemistry

Job Type: Full Time

R&D Project Manager

Job Type: Full Time

Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)

Job Type: Full Time

Copyright 2022 Grove Biopharma. All Rights Reserved.

Senior Scientist, Bioanalytical Chemistry

Location: Fulton Market, Chicago, IL

Job Type: Full Time

About Us:

Grove Biopharma is an early-stage biotech company, pioneering a novel chemistry platform of synthetic biologics – Precision Linked Proteomimetics (PLPs). PLPs are customizable, synthetic, protein-scale molecules for targeting intracellular protein-protein interactions. PLPs display cell permeability, potency and long half-life “out of the box”, bypassing some of the most challenging hurdles of traditional drug discovery workflows. Our research programs focus on addressing significant unmet medical needs in oncology and other rare diseases through targeting select transcription factor protein-protein interactions. 

Job Description:

We are seeking an experienced Senior Scientist in Bioanalytical Chemistry to join our research and development team. This position plays a critical role in advancing our understanding of drug behavior in biological systems through the development and application of cutting-edge bioanalytical techniques. The ideal candidate will have extensive experience in the analysis of biological samples using mass spectrometry and other high-throughput analytical methods. This position offers an exciting opportunity to contribute to the success of our drug discovery programs by developing and validating robust bioanalytical methods for complex biological matrices that can translate from preclinical use into clinical trials.

Key Responsibilities:

  • Develop and validate bioanalytical methods for the quantitative analysis of biological samples, ensuring the accuracy, sensitivity, and reproducibility of results.
  • Utilize advanced mass spectrometry techniques to analyze biological samples, supporting pharmacokinetic, pharmacodynamic, and toxicological studies.
  • Design and execute bioanalytical experiments, analyzing complex data sets to provide insights into the pharmacokinetics and metabolism of drug candidates.
  • Work closely with cross-functional teams, including pharmacologists, toxicologists, and medicinal chemists, to integrate bioanalytical data into the broader drug development process.
  • Oversee the maintenance and operation of bioanalytical instruments, ensuring that all equipment is calibrated and functioning optimally for high-throughput analysis.

Required Skills and Experience:

  • M.S. or Ph.D. in Bioanalytical Chemistry, Analytical Chemistry, or a closely related field.
  • 5+ years of postdoctoral experience required for Ph.D., 10+ years of post-degree experience for M.S. level; experience in pharma or biotech industry strongly preferred.
  • High level of expertise with LC/MS MS and other high-throughput analytical methods for the quantitative analysis of biological samples in complex matrices (e.g., serum, tissue, tumor); experience in bottoms-up proteomics workflows and the analysis of peptide-based modalities strongly preferred.
  • Demonstrated ability to develop and validate bioanalytical methods, ensuring the precision and accuracy required for drug development studies.
  • Excellent collaboration skills, with the ability to work effectively in a multidisciplinary team, and strong written and verbal communication skills for presenting complex scientific data.

Compensation:

  • Salary dependent on experience
  • Annual performance bonus
  • Equity incentive plan

Benefits:

  • Medical, Dental and Vision insurance
  • 401K with company match
  • Paid parental leave benefits
  • Commuter benefit
  • Building amenities including 24h fitness center access and roof top lounge

Grove Biopharma is an equal opportunity employer.  We celebrate diversity and are committed to an inclusive work environment for all employees.

Interested applicants should send CV/resume and cover letter (~1 page) to

careers@grovebiopharma.com

. 

R&D Project Manager

Location: Fulton Market, Chicago, IL

Job Type: Full Time

About Us:

Grove Biopharma is an early-stage biotech company, pioneering a novel chemistry platform of synthetic biologics – Precision Linked Proteomimetics (PLPs). PLPs are customizable, synthetic, protein-scale molecules for targeting intracellular protein-protein interactions. PLPs display cell permeability, potency and long half-life “out of the box”, bypassing some of the most challenging hurdles of traditional drug discovery workflows. Our research programs focus on addressing significant unmet medical needs in oncology and other rare diseases through targeting select transcription factor protein-protein interactions. 

Job Description:

We are seeking an experienced R&D Project Manager to oversee and coordinate all aspects of preclinical drug development through IND filing. The project manager will be responsible for managing detailed project timelines for both internal scientific teams and external CROs, and ensuring projects are delivered on-time and within budget. The ideal candidate will be able to  proactively  identify and resolve potential risks to avoid project delays and will also be well-versed in regulatory requirements in order to facilitate a smooth IND filing process. This is a critical role within our organization, requiring strong project management skills, scientific expertise, and the ability to drive complex projects to successful outcomes.

Key Responsibilities:

  • Oversee and manage all activities related to the preclinical development of drug candidates to enable successful IND filings.
  • Develop and maintain detailed project timelines, tracking progress against key milestones, and ensuring project teams adhere to critical deadlines.
  • Coordinate and manage relationships with contract research organizations (CROs) and other external partners, including contract negotiations and ensuring that deliverables are provided on time.
  • Collaborate closely with internal scientific teams and external partners to ensure seamless communication, alignment of goals, and proper execution of project plans.
  • Proactively identify potential project risks and bottlenecks, escalating issues when necessary and working to resolve them before they lead to delays.
  • Track and manage project budgets, ensuring that all activities are completed within the allocated budget, and providing regular financial updates to leadership.
  • Ensure that preclinical development activities are aligned with regulatory requirements, facilitating a smooth transition to IND filing.
  • Maintain comprehensive project documentation and prepare reports to provide clear communication of project status, risks, and outcomes to senior management and other stakeholders.

Required Skills and Experience:

  • B.S. in Biology, Chemistry, Pharmacology, or related fields required; M.S. or Ph.D. preferred. PMP Certification is a plus but not required.
  • S. with 10+ years of experience or M.S./Ph.D. with 5+ years of scientific project management experience in the pharmaceutical or biotech industries, with experience overseeing/coordinating preclinical development activities through IND filing.
  • Proven ability to manage complex R&D projects, including experience with timeline management, risk identification, and issue escalation.
  • Experience coordinating activities with CROs and external partners, including contract negotiations and performance management.
  • Familiarity with the regulatory requirements and processes involved in IND filing, and experience ensuring compliance with these standards during preclinical development.
  • Excellent written and verbal communication skills, with the ability to clearly articulate project progress, risks, and recommendations to cross-functional teams and leadership.
  • Experience with project management software (e.g., Microsoft Project or similar)

Compensation:

  • Salary dependent on experience
  • Annual performance bonus
  • Equity incentive plan

Benefits:

  • Medical, Dental and Vision insurance
  • 401K with company match
  • Paid parental leave benefits
  • Commuter benefit
  • Building amenities including 24h fitness center access and roof top lounge

Grove Biopharma is an equal opportunity employer.  We celebrate diversity and are committed to an inclusive work environment for all employees.

Interested applicants should send CV/resume and cover letter (~1 page) to:

careers@grovebiopharma.com

. 

Senior Scientist, Drug Metabolism/Pharmacokinetics (DM/PK)

Location: Fulton Market, Chicago, IL

Job Type: Full Time

About Us:

Grove Biopharma is an early-stage biotech company, pioneering a novel chemistry platform of synthetic biologics – Precision Linked Proteomimetics (PLPs). PLPs are customizable, synthetic, protein-scale molecules for targeting intracellular protein-protein interactions. PLPs display cell permeability, potency and long half-life “out of the box”, bypassing some of the most challenging hurdles of traditional drug discovery workflows. Our research programs focus on addressing significant unmet medical needs in oncology and other rare diseases through targeting select transcription factor protein-protein interactions. 

Job Description:

We are seeking an experienced Senior Scientist in Drug Metabolism/Pharmacokinetics (DM/PK) to join our growing research team. This role is crucial for driving the in vivo evaluation of our therapeutic candidates, with a focus on understanding the pharmacokinetics, metabolism, and bioavailability of novel compounds. The ideal candidate will have a deep understanding of DM/PK principles, extensive experience with in vivo testing and animal models. This hands-on role will require working in the lab, as well as designing studies and guiding company strategy as it relates to advancement of our drug discovery pipeline.

Key Responsibilities:

  • Independently design and conduct in vivo studies to assess the pharmacokinetics, metabolism, and bioavailability of drug candidates using various animal models, particularly mouse models for cancer drugs.
  • Develop detailed experimental protocols and manage the review/approval process with IACUC
  • Work closely with interdisciplinary teams, including medicinal chemists and biologists, to integrate DM/PK data into the broader drug discovery and development process.
  • Manage and mentor laboratory technicians, providing guidance on experimental techniques and ensuring the smooth operation of the lab.

Required Skills and Experience:

  • Education: M.S. or Ph.D. in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field
  • Experience: For M.S., 10+ years of relevant postdegree experience in DM/PK studies or 5+ years postdoctoral experience for Ph.D.; industry experience preferred.
  • Strong expertise in preclinical in vivo pharmacokinetic studies, including the design, execution, and analysis of experiments.
  • Extensive experience with performing in vivo studies, including injecting mice with test molecules, euthanizing animals, and collecting organs and blood samples for further analysis, and histology procedures, such as organ processing and H&E staining
  • Experience with data analysis software such as WinNonlin, Phoenix, or similar tools for PK/PD modeling.
  • Proven track record of scientific contributions, such as publications in peer-reviewed journals
  • Excellent problem-solving skills and the ability to work independently as well as part of a multidisciplinary team.
  • Strong communication skills, both written and verbal, with the ability to effectively present complex data

Compensation:

  • Salary dependent on experience
  • Annual performance bonus
  • Equity incentive plan

Benefits:

  • Medical, Dental and Vision insurance
  • 401K with company match
  • Paid parental leave benefits
  • Commuter benefit
  • Building amenities including 24h fitness center access and roof top lounge

Grove Biopharma is an equal opportunity employer.  We celebrate diversity and are committed to an inclusive work environment for all employees.

Interested applicants should send CV/resume and cover letter (~1 page) to:

careers@grovebiopharma.com

. 

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